1982年12月南通大學(xué)醫(yī)學(xué)院醫(yī)學(xué)系本科畢業(yè)，獲醫(yī)學(xué)學(xué)士學(xué)位；1988 年8月山東大學(xué)醫(yī)學(xué)院婦產(chǎn)科學(xué)碩士研究生畢業(yè)，獲醫(yī)學(xué)碩士學(xué)位；2006 年6月浙江大學(xué)醫(yī)學(xué)院婦產(chǎn)科學(xué)博士研究生畢業(yè)，獲醫(yī)學(xué)博士學(xué)位。從1982-至今，一直從事婦產(chǎn)科學(xué)臨床、教學(xué)、科研和管理工作。先后在南通大學(xué)附屬第一醫(yī)院、山東大學(xué)附屬省立醫(yī)院和浙江大學(xué)附屬婦產(chǎn)科醫(yī)院就職。2000-2001年以國(guó)家公派訪問(wèn)學(xué)者身份赴加拿大British Columbia 大學(xué)進(jìn)修學(xué)習(xí)生殖內(nèi)分泌。研究方向： 1、生殖衰老與不孕；2、輔助生殖與優(yōu)生技術(shù)；3、生殖安全與出生缺陷防控。先后參編專著一部；教材二部；公開(kāi)發(fā)表SCI論文20篇；主持國(guó)家自然科學(xué)基金面上項(xiàng)目2項(xiàng)（No. 30471642；No. 81070541）；參與國(guó)家“973”、“863”等重大科研項(xiàng)目和其它國(guó)家及省部級(jí)科研項(xiàng)目多項(xiàng)。
學(xué)術(shù)團(tuán)體和社會(huì)兼職：
1.教育部普通高校五年制醫(yī)學(xué)本科《婦產(chǎn)科學(xué)》教材編委
2.教育部主管《現(xiàn)代婦產(chǎn)科進(jìn)展》雜志編委
業(yè)績(jī)一覽：
一、代表性論著：
1.Zheng YM, Li L, Zhou LM, Le F, Cai LY, Yu P, Zhu YR, Liu XZ, Wang LY, Li LJ, Lou YY, Xu XR, Lou HY, Zhu XM (朱小明), Sheng JZ, Huang HF, Jin F*: Alterations in the frequency of trinucleotide repeat dynamic mutations in offspring conceived through assisted reproductive technology. Hum Reprod 2013, 28(9):2570-80
2.Xu XR, Fu R, Wang LY, Wang N, Zhang F, Le F, Li L, Li LJ, Liu XZ, Zheng YM,. Lou HY, Jiang SW, Zhu XM (朱小明), Huang HF, Jin F*: Epigenetic inheritance of paternally expressed imprinted genes in the testes of ICSI mice. Curr Pharm Des 2013. PMID:2390980
3.Wang LY, Wang N, Le F, Li L, Li LJ, Liu XZ, Zheng YM, Lou HY, Xu XR, Zhu XM (朱小明), Zhu YM, Huang HF, Jin F*: Persistence and intergenerational transmission of differentially expressed genes in the testes of intracytoplasmic sperm injection conceived mice. J Zhejiang Univ Sci B 2013, 14:372-381.
4.Wang LY, Le F, Wang N, Li L, Liu XZ, Zheng YM, Lou HY, Xu XR, Chen YL, Zhu XM (朱小明), Huang HF, Jin F: Alteration of fatty acid metabolism in the liver, adipose tissue, and testis of male mice conceived through assisted reproductive technologies: fatty acid metabolism in ART mice. Lipids Health Dis 2013, 12:5.
5.Wu YT, Wang TT, Chen XJ, Zhu XM (朱小明), Dong MY, Sheng JZ, Xu CM, Huang HF: Bone morphogenetic protein-15 in follicle fluid combined with age may differentiate between successful and unsuccessful poor ovarian responders. Reprod Biol Endocrinol 2012, 10:6.
6.Yin LJ, Zhang Y, Lv PP, He WH, Wu YT, Liu AX, Ding GL, Qu F, Xu CM, Dong MY, Zhu XM (朱小明) and Huang HF: Insufficient maintenance DNA methylation is associated with abnormal embryonic development. BMC Med. 2012 Mar 13;10:26
7.Feng C, Tian S, Zhang Y, He J, Zhu XM (朱小明), Zhang D, Sheng JZ, Huang HF, General imprinting status is stable in assisted reproduction-conceived offspring. Fertil Steril, 2011; 96:1417–23.
8.He RH, Zhu XM (朱小明，通訊作者), How to deal with fluid in the endometrial cavity during assisted reproductive techniques. Curr Opin Obstet Gynecol. 2011; 23(3):190-4.
9.He RH, Gao HJ, Li YQ, and Zhu XM (朱小明，通訊作者), The associated factors to endometrial cavity fluid and the relevant impact on the IVF-ET outcome. Reprod Biol Endocrinol, 2010. 8:46.
10.Tang L, Zhang Y, Pan H, Luo Q, Zhu X-M (朱小明), Dong M-Y, Leung P, Sheng J-Z, and Huang H-F, Involvement of cyclin B1 in progesterone-mediated cell growth inhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell. Reprod Biol Endocrinol, 2009. 7(1):144.
11.Lin K, Zhu X (朱小明), Xu H, Liang Z, Zhang X: Reproductive outcome following resectoscope metroplasty in women having a complete uterine septum with double cervix and vagina. Int J Gynaecol Obstet. 2009;105:25-8
12.Zhu XM (朱小明), Zhu YM, Xu CM, Qian YL, Jin F, and Huang HF, Autologous mature follicular fluid: its role in in vitro maturation of human cumulus-removed oocytes. Fertil Steril, 2008. 90(4):1094-102.
13.Wu YT, Tang L, Cai J, Lu XE, Xu J, Zhu XM (朱小明), Luo Q, Huang HF*: High bone morphogenetic protein-15 level in follicular fluid is associated with high quality oocyte and subsequent embryonic development. Hum Reprod 2007, 22:1526-1531.
14.Liu AX, Zhu YM, Luo Q, Wu YT, Gao HJ, Zhu XM (朱小明), Xu CM, Huang HF: Specific peptide patterns of follicular fluids at different growth stages analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Biochimica Et Biophysica Acta-General Subjects 2007, 1770:29-38.
15.Luo Q, Ning WX, Wu YT, Zhu XM (朱小明), Jin F, Sheng JZ, Huang HF, Altered expression of interleukin-18 in ectopic and eutopic endometrium of women with endometriosis. J Reprod Immunol 2006; 72:108-17
16.Luo Q, Yang J, Zeng QL, Zhu XM (朱小明), Qian YL, Huang HF: 50-Hertz electromagnetic fields induce gammaH2AX foci formation in mouse preimplantation embryos in vitro. Biol Reprod. 2006; 75:673-80
17.Jin L, Zhu XM (朱小明，共同第一作者), Luo Q, Qian Y, Jin F, and Huang HF, A novel SNP at exon 17 of INSR is associated with decreased insulin sensitivity in Chinese women with PCOS. Mol Hum Reprod, 2006. 12:151-5
18.Ruan HC, Zhu XM (朱小明，共同第一作者), Luo Q, Liu AX, Qian YL, Zhou CY, Jin F, Huang HF, and Sheng JZ, Ovarian stimulation with GnRH agonist, but not GnRH antagonist, partially restores the expression of endometrial integrin beta3 and leukaemia-inhibitory factor and improves uterine receptivity in mice. Hum Reprod, 2006. 21:2521-9.
19.朱小明，金帆和黃荷鳳：人自體胚胎干細(xì)胞創(chuàng)建技術(shù)的研究進(jìn)展[J]. 《國(guó)外醫(yī)學(xué)》（計(jì)劃生育分冊(cè)）2006; 25:121-124
20.朱小明，蔡婕和黃荷鳳：卵巢低反應(yīng)的診斷標(biāo)準(zhǔn)和預(yù)測(cè)[J]. 《中國(guó)實(shí)用婦科與產(chǎn)科雜志》 2006; 22:388-390
21.朱小明和黃荷鳳：月經(jīng)的生理和調(diào)節(jié)[J]. 《中國(guó)實(shí)用婦科與產(chǎn)科雜志》 2004; 20:208-209
22.朱小明，黃荷鳳和朱依敏：醫(yī)源性多胎妊娠的倫理問(wèn)題及對(duì)策[J]. 《醫(yī)學(xué)與哲學(xué)》 2003; 22(11):36-38
23.Leung PC, Cheng CK, and Zhu XM (朱小明), Multi-factorial role of GnRH-I and GnRH-II in the human ovary. Mol Cell Endocrinol, 2003, 202:145-53.
24.Lau HL, Zhu XM (朱小明), Leung PC, Chan LW, Chen GF, Chan PS, Yu KL, and Chan FL, Detection of mRNA expression of gonadotropin-releasing hormone and its receptor in normal and neoplastic rat prostates. Int J Oncol, 2001. 19:1193-201.
25.朱小明，等：甲氨蝶呤和丙酸睪丸酮輔助加強(qiáng)藥物流產(chǎn)的臨床觀察?！冬F(xiàn)代婦產(chǎn)科進(jìn)展》2001；10:55~57
26.朱小明，等：婦產(chǎn)科學(xué)臨床實(shí)習(xí)教學(xué)和管理的研究報(bào)告?！吨袊?guó)高等醫(yī)學(xué)教育》1999；（5）:59~61
27.朱小明：人工破膜后暫緩靜點(diǎn)催產(chǎn)素的引產(chǎn)方法探討?！吨袊?guó)實(shí)用婦科與產(chǎn)科雜志》1992；8:203~205
二、承擔(dān)課題：
1.國(guó)家重大科學(xué)研究計(jì)劃（2012CB944900）：輔助生殖誘發(fā)胚胎源性疾病的風(fēng)險(xiǎn)評(píng)估和機(jī)制研究，科技部，起止時(shí)間：2012-2016，研究骨干
2.國(guó)家自然科學(xué)基金面上項(xiàng)目（81070541）：輔助生殖子代低出生體重的基因組印記狀態(tài)及發(fā)病機(jī)制研究，2011-2013，課題負(fù)責(zé)人
3.國(guó)家自然科學(xué)基金面上項(xiàng)目（30671161）：輔助生殖技術(shù)出生的子代基因組印記表達(dá)譜的變化及其機(jī)制研究，2007-2009，課題負(fù)責(zé)人
4.國(guó)家自然科學(xué)基金—中加健康研究合作計(jì)劃項(xiàng)目（30711120577）：卵細(xì)胞源性生長(zhǎng)因子對(duì)人類卵泡發(fā)育調(diào)節(jié)機(jī)制的研究，2008.1-2010.12，研究骨干
5.國(guó)家科技部863課題（20060102A1022）：我國(guó)人類（疾病）胚胎干細(xì)胞庫(kù)的建立與應(yīng)用，2007-2011，研究骨干
6.國(guó)家自然科學(xué)基金面上項(xiàng)目（30471642）：親緣性基因印記校正的雌核發(fā)育/雄核發(fā)育技術(shù)創(chuàng)建人自體胚胎干細(xì)胞的研究，2005-2007，研究骨干
三、出版物編寫
1.《其它內(nèi)分泌疾病與閉經(jīng)》。見(jiàn)陳子江和林金芳主編：（中華醫(yī)學(xué)會(huì)繼續(xù)醫(yī)學(xué)教育教材）《閉經(jīng)診斷治療指南及解讀》. 北京. 清華同方光盤電子出版社. 2012-07-01：P47~52 （ISBN 978-7-89477-323-4）
2.《第七章 人類生殖工程技術(shù)應(yīng)用中的倫理學(xué)問(wèn)題及相關(guān)法律法規(guī)》。見(jiàn)喬杰主編：（全國(guó)高等學(xué)校教材）《生殖工程學(xué)》. 北京. 人民衛(wèi)生出版社. 2007：P213~223 （ISBN 978 - 7 -117 – 08886 – 2/R.8887）
3.《第四章 妊娠生理》和《第五章 妊娠診斷》。見(jiàn)孔北華主編：（全國(guó)高等學(xué)校醫(yī)學(xué)規(guī)劃教材）《婦產(chǎn)科學(xué)》. 北京. 高等教育出版社. 2005：P33~53 （ISBN 7 - 04 -016773 – 5）
主攻學(xué)科：生殖內(nèi)分泌、輔助生殖和計(jì)劃生育
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